<b>Cyclic changes in cytoplasmic free Ca<sup>2+</sup> during membrane potential oscillations in </b><b>fibroblasts </b>
نویسندگان
چکیده
منابع مشابه
Glucose-induced oscillations in cytoplasmic free Ca2+ concentration precede oscillations in mitochondrial membrane potential in the pancreatic beta-cell.
Using dual excitation and fixed emission fluorescence microscopy, we were able to measure changes in cytoplasmic free Ca(2+) concentration ([Ca(2+)](i)) and mitochondrial membrane potential simultaneously in the pancreatic beta-cell. The beta-cells were exposed to a combination of the Ca(2+) indicator fura-2/AM and the indicator of mitochondrial membrane potential, rhodamine 123 (Rh123). Using ...
متن کاملRole of Oscillations in Membrane Potential, Cytoplasmic Ca , and Metabolism for Plasma Insulin Oscillations
A model for the relationship between ionic and metabolic oscillations and plasma insulin oscillations is presented. It is argued that the pancreatic -cell in vivo displays two intrinsic frequencies that are important for the regulation of plasma insulin oscillations. The rapid oscillatory activity (2–7 oscillations [osc] per minute), which is evident in both ionic and metabolic events, causes t...
متن کاملRole of oscillations in membrane potential, cytoplasmic Ca2+, and metabolism for plasma insulin oscillations.
A model for the relationship between ionic and metabolic oscillations and plasma insulin oscillations is presented. It is argued that the pancreatic beta-cell in vivo displays two intrinsic frequencies that are important for the regulation of plasma insulin oscillations. The rapid oscillatory activity (2--7 oscillations [osc] per minute), which is evident in both ionic and metabolic events, cau...
متن کاملMembrane potential changes during chemokinesis in Paramecium.
Intracellular recordings show that (i) paramecia hyperpolarize slightly in attractants and depolarize in repellents that depend on the avoiding reaction (an abrupt change of swimming direction), and (ii) paramecia more strongly hyperpolarize in repellents and more strongly depolarize in attractants that depend on changes of swimming velocity. These membrane potential changes are in agreement wi...
متن کاملAcetylcholine-Induced Membrane Potential Oscillations
RESULTS. Acetylcholine (100 nM to 1 mM) induced a decrease in membrane conductance and a depolarization of membrane potential in the intact lens. The responses were reversed by application of the muscarinic antagonist, atropine (1 /xM to 100 /xM). In the presence of 1 JLLM thapsigargin and 30 JUM cyclopiazonic acid, acetylcholine still induced an electrical response. Long exposures to acetylcho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedical Research
سال: 1983
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.4.231